Differentiation of Low-Grade Astrocytoma From Anaplastic Astrocytoma Using Radiomics-Based Machine Learning Techniques

Anaplastic astrocytoma post radiotherapy of pineal germinoma.

Dra. Martha Tena-Suck – Departamento de Neuropatología / Instituto Nacional de Neurología y Neurocirugía “Manuel Velasco Suárez” Av. Insurgentes Sur, 3788 Col. La fama, Delegación Tlalpan C.P. 14269 México DF México. E-mail: [email protected] Intracranial germ cell tumors (GCTs), especially pineal tumors have attracted the special attention of neuropathologists and neurosurgeons because of ...

The genetic landscape of anaplastic astrocytoma

Anaplastic astrocytoma WHO grade III (A3) is a lethal brain tumor that often occurs in middle aged patients. Clinically, it is challenging to distinguish A3 from glioblastoma multiforme (GBM) WHO grade IV. To reveal the genetic landscape of this tumor type, we sequenced the exome of a cohort of A3s (n=16). For comparison and to illuminate the genomic landscape of other glioma subtypes, we also ...

Molecular genetic analysis of paediatric low-grade astrocytoma

Acquired stuttering due to recurrent anaplastic astrocytoma.

Acquired (neurogenic) stuttering is a rare phenomenon seen after cerebral infarction or brain injury. Aetiology of this symptom is unclear, but recent evidence supports that it is a disturbance in the left hemispheric neural network involving the interplay between the cortex and basal ganglia. We present the case of a patient who develops acquired stuttering after a recurrence of a right tempor...

Factors predicting progression of low-grade diffusely infiltrating astrocytoma.

BACKGROUND Low-grade diffuse astrocytoma (DA) is considered benign tumor (World Health Organization [WHO] grade II), but it has an inherent tendency for malignant progression, which is quite variable. AIM To identify malignant progression in an individual case of DA, we studied the clinico-radiological and immunohistochemical factors and correlated with progression of DA at a dedicated tertia...